Microbiology and Immunology

Tumor Immunology

Tumor immunology is the study of the interaction between immune function and tumour cells, which is important for understanding the causes of tumour rejection and progression. The immunological pathways underlying cancer progression are extremely complicated, encompassing both tissue-resident and blood-derived cells. The human immune system mounts a natural endogenous response to highly immunogenic tumour cells via a series of steps that include presenting tumor antigens to T cells via antigen-presenting cells (APCs), priming and activating T cells in lymph nodes, trafficking and infiltration of T cells into tumour beds, recognition of cancer cells by T cells, development of antigen-specific effector and memory T cells, and humoral immunity, which allows effector T cells and memory T cells to interact.Vaccines And Immunotherapy