Metabolic engineering

Metabolic engineering means production of fuels, pharmaceuticals and drugs for human welfare by altering metabolic pathways. This method involves overexpression or downregulation of certain proteins such that it gives a new product. The primary step is the understanding of host cell genetic makeup followed by it’s effect on growth of microorganism. The environmental conditions are considered for desired phenotype is called inverse metabolic engineering. Various recombinant DNA technology approaches are used for the production of secondary metabolite improvement.

  • Heterologous expression of gene clusters
  • Gene insertion and deletion
  • production of amino acids, biofuels
  • metabolic engineering of plant derived anti-cancer drugs.
  • Strain improvement for production of biofuels from algae

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